Photoinduced cytotoxicity of a photochromic diarylethene via caspase cascade activation.
نویسندگان
چکیده
The photo-generated closed-ring isomer of bis(5-methyl-2-phenylthiazoyl)perfluorocyclopentene shows cytotoxicity to Madin-Darby canine kidney (MDCK) cells through a caspase cascade and induces apoptosis of cells.
منابع مشابه
Photoinduced micropatterning by polymorphic crystallization of a photochromic diarylethene in a polymer film.
A photochromic diarylethene was found to crystallize rapidly from the amorphous state in poly(methyl methacrylate) by heating at 130 degrees C. The diarylethene amorphous film was successfully patterned to form microcrystals upon ultraviolet (UV) light irradiation through a photomask, showing a high resolution as good as approximately 4 microm under optimal conditions.
متن کاملPhotochromism of diarylethene molecules and crystals
Photochromism is defined as a reversible transformation of a chemical species between two isomers upon photoirradiation. Although vast numbers of photochromic molecules have been so far reported, photochromic molecules which exhibit thermally irreversible photochromic reactivity are limited to a few examples. The thermal irreversibility is an indispensable property for the application of photoc...
متن کاملDependence of photoinduced bending behavior of diarylethene crystals on irradiation wavelength of ultraviolet light.
The dependence of the photoinduced bending behavior of diarylethene crystals on the ultraviolet light irradiation wavelength was investigated. When irradiated with 365 nm light, a crystal of 1,2-bis(5-methyl-2-phenyl-4-thiazolyl)perfluorocyclopentene (1a) bends toward the incident light. On the other hand, when irradiated with 380 nm light, the crystal of 1a first bends away from the light sour...
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Hybrid materials combining gold nanoparticles (GNP) of variable diameter and an organic thin layer of photochromic diarylethenes were achieved. Solid-state photoswitching based on ring-closure/ring-opening reaction was carried out under alternate UV and visible irradiations. In addition to the spectral changes due to the photochromism itself, the surface plasmon resonance related to the GNP is ...
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عنوان ژورنال:
- Chemical communications
دوره 51 54 شماره
صفحات -
تاریخ انتشار 2015